Our co-packing and order fulfillment services package and ship products coast to coast. The most common structures using the super barrier PVDC are triplex configurations 250 PVC/25 PE/120gsm PVDC up to 250 PVC/25 PE/180gsm PVDC, with WVTR of 0,11 down to 0,06 g/m2/day and available from various suppliers. The card is colored and designed depending on the item inside, and the PVC is affixed to the card using heat and pressure to activate an adhesive (heat seal coating) on the blister card. [citation needed]. The information in this article is truly just scratching the surface of all there is to know about knurling operations. In some parts of the world the pharmaceutical blister pack is known as a push-through pack (PTP), an accurate description of two key properties (i) the lidding foil is brittle, making it possible to press the product out while breaking the lidding foil and (ii) a semi-rigid formed cavity being sufficiently collapsible to be able to dispense the tablet or capsule by means of pressing it out with the thumb. The aluminum will be elongated and maintain the formed shape. Each one has its unique qualities and price points, from entry level to high end. 8 Top Tips for achieving a Brilliant Blister Seal, Founded in 1980, Sepha has established a global reputation for innovation and development of specialised, high-quality equipment for use in the manufacture of pharmaceutical blister packs, parenterals, medical devices and healthcare products. aH{pZ'sGr5dZq(zH5'9JL,X:0v13N`4} ( 6@ P?*o cq"G[J?w?PbFCS HUZW"*Z}lg>/u*R#:c(-W: y&T=]Z_E8.(USWf-L%`9wKE2\yh&M.|c^L9w?U:FlCP)vAWG'Ecys||k](P'mu$t775 Qs9vIt7{7N6S4xls O_LUq8AhL Blister packs can provide barrier protection for shelf life requirements, and a degree of tamper resistance. Strip size: Measure the length and width of strip and verify the results with the values given in packaging technical directions. The knurling application can also be used so that serrated edges of workpieces can come together in certain unit assemblies. The card is simply slid into place and is sometimes secured with a staple. In other parts of the world, blister packs are the main packaging type since pharmacy dispensing and re-packaging are not common. gp([t&&jE&R-Hg:'}! 1. 0000038579 00000 n Primary packaging: Primary packing is the material that carries the drug product or fills the drugs inside. This is achieved by a rotating tool that impressions the desired pattern into the metal. The main disadvantages are the poor barrier against moisture ingress and oxygen ingress. Material is certainly displaced, however it is more like an impression and is particularly useful for smaller workpieces. Buy your blisters from us, and get a discount on a blister sealer! Tri-Fold clamshells are typically more expensive and have higher tooling costs than other types of clamshells. How the Heat Sealing Process for Blister Packs Work The front card has a die cut hole for the blister shape to come through. Different projects will require completely different knurling criteria. Due to the Tracking Correction Factor (C.F. Knurling Wheel Sets are also available. The PVC side is on the inside in contact with the product. Selecting your sealing system. 0000001677 00000 n This has been a part of my tutorial series called How to Buy Packaging 101. Concerning pharma packaging, the material being used is as important a factor as the compounds being used in the production of the pill or capsule. is essentially the same process just not as severe. Seven steps to blister sealing success | Healthcare Packaging Forming a deeper, wider impression the first time around helps to assure that the teeth will track into the initial grooves for all subsequent revolutions. The diameter of your workpiece will change after your knurling process. Double Trapped Blister Double trapped blister package provides visibility of the front and back of your product with two blisters; one emerging through the front card and a second emerging through the back card. 0000021977 00000 n A great packaging session when youre making blisters requires patience, right calculation and technical help. For this reason, there are many formulas that will help you to calculate the depth of cut, tracking pitch and cutting parameters in combination with the given material. The knurl shape refers to the leading edge of the knurl wheel and the applications it best supports. I hope this gives you a basic idea of the different types of blister packaging as well as some popular blister alternatives. Blister packs are created by means of a form-fill-seal process at the pharmaceutical company or designated contract packer. It is done by using hardened metal wheels with special shapes to enhance the workpiece's appearance and provide a better grip. Trapped blister packaging. Advertising space [ edit] There is a wide range of colors and finishes that blister packaging can be constructed to feature. of Knurl Diametral pitch knurls are designed to permit accurate tracking on standard fractional sized blanks. Convex knurls on the other hand have a sharp leading edge to provide a very smooth and precise finish. This article describes the main types, categorized as follows: Strip Packing Machine High Speed Tablet Strip Packing Machine Automatic/Soft Double Al Strip Packing Machine The most errors that occur with the forming and sealing procedures occur due to wrong temperatures and pressure. If a high surface finish is required, knurl forming is the way to go. 0000018770 00000 n Blister packs refer to a variety of packaging that have a preformed plastic pocket or shell (where a product sits securely in place) that is most often heat sealed to an adhesive coated paperboard card or foil backing (think single dose pills or lozenges). Blister pack - Wikipedia 0000017030 00000 n Customers get a full 360 view of the product. Blister packaging is widely used across the pharmaceutical industry as a unit-dose packaging solution that helps people take the correct amount of medication at the right time. Perhaps you have decided you want to switch up your knurling pattern. This female diamond knurl wheel should be used to create male diamond knurls. Single-Seal Blister Card Available in a variety of seal types, a single-seal is coated and heat-sealed to a thermoformed blister part. Also, there are various substrates, materials and heat-sealing method for blister packaging. Once the knurl wheel has reached the depth, it will take several revolutions to complete the knurling operation. Also, the PVC layer can be colored with pigments and/or UV filters. The primary component of a Thermoforming blister pack is a cavity or pocket made from a formable plastic, usually a thermoformed plastic. Blister Packaging vs Bottles for Pharmaceutical Products, Procedures and Machinery Used in Pharmaceutical Sampling, Accurate format parts for your machines are necessary. endstream endobj startxref PDF Pharmaceutical Blister Packaging, Part I [citation needed], In thermo cold forming process, the first packing is done by thermoforming technique after which the product is repacked with a cold forming package. A series of blister cavities is sometimes called a blister card or blister strip as well as blister pack. A Guide to Blister & Clam Packaging | WePack All Rights Reserved. *)Or# Teeth [part] = (Blank Dia. They instead use plastic films that are more flexible and yet still very durable. 'Is an alu alu blister the best choice for your product? Which makes regular maintenance of format parts important. The lidding foil is coated with a heat-seal lacquer on the inside and a print primer on the outside. The sealing system will have an important bearing on the quality of the seal. It completely blocks the passage of light and entry of unwanted odours. [6][7] Leaving the expiry or best before dates obsolete. 8 Top Tips for achieving a Brilliant Blister Seal - Sepha Choose the Right Blister Packaging for Your Business - Bizongo Your email address will not be published. Please enter valid partnumber and quantity. Some medical device blister packs, for example, are sterilised via gamma radiation, which in some instances can compromise seal integrity. 0000007019 00000 n Multi-layer blister films based on PVC are often used for pharmaceutical blister packaging, whereby the PVC serves as the thermoformable backbone of the structure. The information in this article is truly just scratching the surface of all there is to know about knurling operations. The Global Pharmaceutical Blister Packaging Tooling market is anticipated to rise at a considerable rate during the forecast period, between 2022 and 2030. The knurled blank should be close to the collet and large enough in diameter to prevent deflection. Types of Packaging - The Blister Pack "Blister pack" is a general term that describes packaging that uses a process known as thermoforming. They are used to create a raised diamond design. Aclamshellis a container withtwo halves that are hinged to open and close, just like a clam. We supply packaging equipment parts anywhere in the continental US. Leak test: perform leak test as per the approved procedure. From safety precautions to single or double wheel knurling and knurling best practices, you can dive much deeper and continue your knurling research here. Duplex structures are typically PVC/PVDC films, ranging from 250PVC/40gsmPVDC to 250PVC/120gsmPVDC with WVTR from 0,65 to 0,25 g/m2/d and OTR from 1 to 0,1 cc/m2/d. 0000014180 00000 n The most common lidding foil with push-through features is 20 hard tamper aluminum, which can be supplied pinhole-free from the producers. On the other hand, the blister cavity must remain accessible by the push-through effect and the formed web may not be too hard to collapse when pressed upon; for this reason the PVC sheet thickness is typically chosen between 200 to 300 depending on the cavity size and shape. From four decades of advising pharmaceutical operations on preventing and testing for leaky blister seals, we have amassed a great deal of knowledge around blister pack integrity and how to avoid seal issues. 0000021392 00000 n Stretch Paks can stand on their own on store shelves or be hung using a die-cut hang hole. Types of Blister Packaging - AIPAK Korsch to Present Enhanced 4th Generation Tablet Press, Triumphs and Challenges in Sustainability, Healthcare Packaging News Roundup: Sustainability, Healthcare Packaging's Most Popular Articles, Healthcare's Sustainability Approach: Waste Reduction. This is because the material goes through a lot of physical strain passing through heat, pressure or alterations to chemical formations. Depending on the way in which these variations are selected and applied, hundreds of unique approaches to knurling are possible. A tamper-evident package, according to the regulations of the Food and Drug Administration (21 CFR 211.132), "is one having one or more indicators or barriers to entry which, if breached or missing, can reasonably be expected to provide visible evidence to consumers that tampering has occurred". They are self-centering can be easily adjusted due to having a set of pins and screws to help keep the knurls on the holder. The first reason is aesthetic as knurling is a decorative finishing process that develops a texture on the given workpiece. The high speed steel allows this wheel to perform well in general purpose applications for both ferrous and nonferrous materials. Hello there if you are still looking for a blister packaging, try searching by the technical style and or the material you seek if known. counterfeiting or tampering. = # Teeth [part] / D.P. More than half of shoppers believe it is important to see a product through its packaging. These vary in sensitivity, technology and cost, and include blue dye, helium trace gas, force decay and laser/vision deflection. Wrap rage is sometimes the result. Duplex structures are PVC/PCTFE and triplex laminates are PVC/PE/PCTFE. 0000026340 00000 n %PDF-1.4 % Diametral pitch is based on the number of teeth per inch of the wheels diameter. It can be used as a security package to deter package pilferage for small high-value items, such as consumer electronics. There are many types and variations of blister packs in use in the retail market. The seal is only on the flange while the rest of the card stays uncovered. They are designed to permit accurate tracking on standard fractional sized blanks. EZ Blister+ - A 21 CFR Part 11 compliant blister pack machine for pharmaceutical companies that require low volumes of high-quality blister packs Beveled knurl wheels have a blunt leading edge to spread out loading. endstream endobj 234 0 obj <>/AGFA_NORN_V(ES15.101 V03)/AGFA_PSE_V(Apogee Norm PSE 1.1 23 )/AcroForm 242 0 R/JT 222 0 R/Metadata 157 0 R/PageMode/UseThumbs/Pages 211 0 R/Type/Catalog>> endobj 235 0 obj <> endobj 236 0 obj <>stream So the different materials used for different drugs must be known to both the operator and the person who gives a go ahead for the packaging process to begin. The top card is die cut to fit the blister where the product sits. The machine has a range of options that can be selected to tailor and format the machine to meet individual commercial, manufacturing and technological requirements. Checkout our packaging and processing solutions finder, ProSource. Determining Blank Diameter and the Number of Teeth that will be Rolled For Circular pitch knurls:Blank Dia. There are two pitch systems for specifying tooth spacing on a knurl. 0000038106 00000 n It consists of one sheet folded over onto itself and sometimes fused at the edges. The card is then folded in half and sealed onto itself, so the product is essentially sandwiched between the two cards halves. Typical WVTR values are 0.060.40 g/m2/day. Camera-based integrity testing offers pharmaceutical packaging operations increased efficiencies by utilising non-destructive techniques as part of theprocess. Blister packaging has many construction options to create the perfect package for your product. They are used on steel, brass, aluminum alloys and hard plastics. Type of material (both of wheel and workpiece). Blister packaging is made using several types of rugged polymers, including: Polyethylene terephthalate (PET) Polyvinyl chloride (PVC) Polyvinylidene chloride (PVDC) Tertiary packing: A Tertiary is used for bulk handling of drugs like storage in a warehouse. The embossed patterns can be decorative, but more often act as hand grips and are commonly seen on handles, knobs or rollers. This approach is most ideal for medium to large machining projects that require shoulderless diameter* knurling. These methods can be based on melting and joining of sealant layers using heat sealing or on the application of a cold-seal adhesive coating to the inner surface of the packaging film.2Heat sealing is the most common method, which has been used for decades to shape and close the plastic packaging materials in the food industry. Aspects of packaging 1.1 General considerations Packaging may be dened as the collection of different components (e.g. Since trapped blisters do not use heat sealing, no expensive heat seal tooling is required. endstream endobj 348 0 obj 1284 endobj 298 0 obj << /Type /Page /Parent 291 0 R /Resources 299 0 R /Contents 310 0 R /MediaBox [ 0 0 576 774 ] /CropBox [ 0 0 576 774 ] /Rotate 0 >> endobj 299 0 obj << /ProcSet [ /PDF /Text /ImageC ] /Font << /F6 306 0 R /F8 301 0 R /F9 305 0 R /F11 303 0 R /F13 308 0 R /F18 315 0 R /F21 313 0 R /F23 319 0 R /F25 318 0 R /F30 326 0 R /F33 325 0 R /F36 324 0 R >> /XObject << /Im1 345 0 R >> /ExtGState << /GS1 346 0 R /GS2 336 0 R /GS3 335 0 R >> >> endobj 300 0 obj << /Type /FontDescriptor /Ascent 750 /CapHeight 750 /Descent -189 /Flags 262176 /FontBBox [ -168 -250 1113 1000 ] /FontName /KJPHEH+Helvetica-Condensed-Black /ItalicAngle 0 /StemV 159 /XHeight 560 /CharSet (/i/t/u/m/l/n/y/o/c/T/e/P/space/r/a/h/g) /FontFile3 328 0 R >> endobj 301 0 obj 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